Your question is very personal, But to answer it, here is the case study:

Objective

We sought to understand how trends in Down Syndrome rates have changed by race/ethnicity in the United States from 2012 to 2018.

Study Design

We performed a retrospective cohort study of 26,433,380 pregnancies that occurred in the US between 2012-2018 using linked vital statistics data. We used Cochrane-Armitage tests to assess trends in Down Syndrome diagnosis by race/ethnicity and multivariable logistic regressions to compare Trisomy 21 diagnoses between race/ethnic groups at each year while controlling for maternal age, insurance, education, and ≥ 5 prenatal visits.

Results

Our cohort consisted of 13,788 pregnancies with a diagnosis of Down Syndrome (0.05%) and 26,419,592 (99.95%) with no diagnosis of Down Syndrome. Among the whole cohort (p\< 0.001) and those who identify as Black (p=0.002), Hispanic (p\< 0.001), or American Indian/Alaska Native (AIAN) (p=0.04) Down Syndrome diagnoses increased over time (Figure 1). Among those who identify as white (p=0.55) or Asian (p=0.11), Down Syndrome diagnosis did not change. When adjusting for confounders, in 2012, individuals who identify as Black (aOR 0.56; 95% CI 0.46-0.67), Hispanic (aOR 0.73; 95% CI 0.63-0.84), or Asian (aOR 0.51; 95% CI 0.40-0.66) had lower odds of Down Syndrome diagnoses when compared to white individuals. By 2018 only Asian individuals continued to have lower odds of Down Syndrome diagnosis (aOR 0.50; 95% CI 0.39-0.63) when compared to those identified as white (Table 1).

Conclusion

Down Syndrome rates increased over time among individuals who identify as Black, Hispanic, or AIAN, but not among white or Asian individuals.Whether accessing and navigating changes in Down syndrome testing is contributing to these disparities in outcomes needs further study.

DOI:https://doi.org/10.1016/j.ajog.2021.11.797

Komen er bij mensen met een donkere huidskleur ook mensen voor met het syndroom van Down?